A new flavonoid glycoside from the root bark of Morus alba L

Nat Prod Res. 2014;28(21):1859-63. doi: 10.1080/14786419.2014.951852. Epub 2014 Aug 30.

Abstract

A new guibourtinidol glycoside, (2R,3S)-guibourtinidol-3-O-α-d-apiofuranosyl-(1 → 6)-O-β-D-glucopyranoside (1), and three known compounds, quercetin 7-O-β-D-glucopyranoside (2), syringaresinol-4-O-β-D-glucopyranoside (3) and dehydrodiconiferyl alcohol 4,9'-di-O-β-D-glucopyranoside (4), were isolated from the root bark of Morus alba L. through repeated silica gel, octadecyl silica gel and Sephadex LH-20 column chromatography for the n-BuOH fraction. The chemical structure of the compounds was elucidated based on MS, infrared, 1D and 2D NMR spectroscopic data. Compounds 2-4 were also isolated for the first time from the root bark of M. alba L. in this study.

Keywords: Morus alba L; flavonoid; guibourtinidol glycoside; lignan.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Flavonoids / chemistry
  • Flavonoids / isolation & purification*
  • Glycosides / chemistry
  • Glycosides / isolation & purification*
  • Morus / chemistry*
  • Nuclear Magnetic Resonance, Biomolecular
  • Plant Bark / chemistry
  • Plant Roots / chemistry
  • Republic of Korea

Substances

  • (2R,3S)-guibourtinidol-3-O-alpha-D-apiofuranosyl-(1-6)-O-beta-D-glucopyranoside
  • Flavonoids
  • Glycosides