Synthesis of the first amphiphilic pillar[6]arene and its enzyme-responsive self-assembly in water

Chem Commun (Camb). 2014 Oct 14;50(80):11954-6. doi: 10.1039/c4cc05621c.

Abstract

The first amphiphilic pillar[6]arene was successfully synthesized. It can complex with adenosine triphosphate to form vesicles in water. Moreover, these vesicles are efficiently responsive to phosphatase.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / chemistry
  • Adenosine Triphosphate / metabolism
  • Drug Compounding
  • Hydrolysis
  • Micelles*
  • Phosphoric Monoester Hydrolases / metabolism
  • Quaternary Ammonium Compounds / chemistry*
  • Surface-Active Agents / chemical synthesis*
  • Surface-Active Agents / chemistry
  • Water / chemistry

Substances

  • Micelles
  • Quaternary Ammonium Compounds
  • Surface-Active Agents
  • pillar(6)arene
  • Water
  • Adenosine Triphosphate
  • Phosphoric Monoester Hydrolases