Past blood alcohol concentration and injury in trauma center: propensity scoring

J Emerg Med. 2014 Oct;47(4):387-94. doi: 10.1016/j.jemermed.2014.06.024. Epub 2014 Aug 23.

Abstract

Background: Evidence linking alcohol use to injury outcomes remains inconclusive, with prehospital and police department-based studies showing negative effects and hospital-based studies showing no effect or better outcomes.

Objective: The purpose of this study was to examine the relationship of blood alcohol concentration (BAC) with injury characteristics and outcomes among trauma patients admitted to a major teaching hospital. In an effort to mitigate selection and confounding bias, propensity scoring methodology was applied, by which trauma patients were randomly assigned to high- and low-BAC groups.

Methods: Electronic medical records were retrospectively reviewed for a period of 8 months. Of 1057 patients whose BAC was determined, 667 had BAC ≤ 0.08 g/dL and 390 had BAC > 0.08 g/dL. Injury characteristics were defined as injury type, injury location, and trauma level. Injury outcomes were defined as hospitalization, length of hospital stay, and in-hospital death. Adjusted odds ratios (aOR) and their 95% confidence intervals (CI) were calculated using multivariate logistic regression models and propensity scoring was applied.

Results: A positive relationship was observed between BAC and unintentional injury (aOR = 1.08; 95% CI 1.01-1.17). Although injuries of the extremities were less likely to occur in patients with high BAC (aOR = 0.88; 95% CI 0.80-0.98), head injury was positively associated with high BAC (aOR = 1.27; 95% CI 1.14-1.42). Also, Level I trauma patients had nearly 60% greater odds of having a high BAC than Level II trauma patients.

Conclusions: A high alcohol level in the blood appears to be predictive of more unintentional injury, head injury, and Level I trauma activation and less injuries in extremities.

Keywords: alcohol; death; hospitalization; injury; trauma.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Alcohol Drinking / adverse effects
  • Alcohol Drinking / blood*
  • Biomarkers / blood
  • Central Nervous System Depressants / blood*
  • Ethanol / blood*
  • Female
  • Hospital Mortality
  • Hospitalization / statistics & numerical data
  • Humans
  • Injury Severity Score
  • Length of Stay / statistics & numerical data
  • Logistic Models
  • Male
  • Middle Aged
  • Predictive Value of Tests
  • Propensity Score
  • Retrospective Studies
  • Trauma Centers / statistics & numerical data*
  • United States / epidemiology
  • Wounds and Injuries / blood*
  • Wounds and Injuries / mortality
  • Young Adult

Substances

  • Biomarkers
  • Central Nervous System Depressants
  • Ethanol