Vaccinating the inflammatory bowel disease patient

Expert Rev Gastroenterol Hepatol. 2015 Jan;9(1):91-102. doi: 10.1586/17474124.2014.934672. Epub 2014 Aug 27.

Abstract

Current therapeutic options for patients with inflammatory bowel disease (IBD) include several agents that can alter their immune response to infections. Effective vaccines exist and offer protection against a number of infectious diseases. However, recent data has shown that IBD patients are inadequately vaccinated and, as a result, at risk to develop certain preventable infections. Furthermore, gastroenterologists' knowledge regarding the appropriate immunizations to administer to their IBD patients is suboptimal. This review article focuses on the current immunization schedule for the IBD patient and stresses the important role of the gastroenterologist as an active participant in the management of vaccination in their IBD patients.

Keywords: Crohn’s disease; HPV; PCV 13; PPSC23; hepatitis A; hepatitis B; immunocompromised; infections; inflammatory bowel disease; travel; ulcerative colitis; vaccination; varicella; zoster.

Publication types

  • Review

MeSH terms

  • Bacterial Infections / diagnosis
  • Bacterial Infections / immunology
  • Bacterial Infections / microbiology
  • Bacterial Infections / prevention & control*
  • Bacterial Vaccines / administration & dosage
  • Bacterial Vaccines / immunology
  • Bacterial Vaccines / therapeutic use*
  • Humans
  • Immunization Schedule
  • Immunocompromised Host
  • Immunosuppressive Agents / adverse effects*
  • Inflammatory Bowel Diseases / diagnosis
  • Inflammatory Bowel Diseases / drug therapy*
  • Inflammatory Bowel Diseases / immunology
  • Risk Factors
  • Treatment Outcome
  • Vaccination*
  • Viral Vaccines / administration & dosage
  • Viral Vaccines / immunology
  • Viral Vaccines / therapeutic use*
  • Virus Diseases / diagnosis
  • Virus Diseases / immunology
  • Virus Diseases / prevention & control*
  • Virus Diseases / virology

Substances

  • Bacterial Vaccines
  • Immunosuppressive Agents
  • Viral Vaccines