Abstract
Phpy bridged homodinuclear Ru-Ru () and heterodinuclear Ir-Ru complexes () have been developed. Complex induces autophagy towards the cisplatin resistant human breast cancer (MCF7) cell line, whereas is inactive.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents / chemical synthesis*
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Antineoplastic Agents / chemistry
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Antineoplastic Agents / pharmacology*
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Autophagy / drug effects*
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Cell Line, Tumor
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Cisplatin / chemistry
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Cisplatin / pharmacology
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Coordination Complexes / chemical synthesis*
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Coordination Complexes / chemistry
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Coordination Complexes / pharmacology
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Drug Resistance, Neoplasm / drug effects*
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Humans
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Molecular Structure
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Optical Imaging
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Ruthenium / chemistry*
Substances
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Antineoplastic Agents
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Coordination Complexes
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Ruthenium
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Cisplatin