Calibration of qualitative HBsAg assay results for quantitative HBsAg monitoring

Hans Gunning; Dena Adachi; Julian W Tang

doi:10.1016/j.jcv.2014.07.017

Calibration of qualitative HBsAg assay results for quantitative HBsAg monitoring

J Clin Virol. 2014 Oct;61(2):305-8. doi: 10.1016/j.jcv.2014.07.017. Epub 2014 Aug 4.

Authors

Hans Gunning¹, Dena Adachi¹, Julian W Tang²

Affiliations

¹ Alberta Provincial Laboratory for Public Health, Edmonton, Alberta, Canada.
² Alberta Provincial Laboratory for Public Health, Edmonton, Alberta, Canada; Department of Medical Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada. Electronic address: Julian.Tang@albertahealthservices.ca.

PMID: 25153901
DOI: 10.1016/j.jcv.2014.07.017

Abstract

Evidence is accumulating that quantitative hepatitis B surface antigen monitoring may be useful in managing patients with chronic HBV infection on certain treatment regimens. Based on these results with the Abbott Architect qualitative and quantitative HBsAg assays, it seems feasible to convert qualitative to quantitative HBsAg values for this purpose.

Keywords: HBV; HBsAg; Hepatitis B; Qualitative; Quantitative; Surface antigen.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Antiviral Agents / therapeutic use
Calibration
Clinical Laboratory Techniques / standards*
Drug Monitoring / standards*
Hepatitis B Surface Antigens / blood*
Hepatitis B, Chronic / diagnosis*
Hepatitis B, Chronic / drug therapy
Humans
Immunoassay / standards

Substances

Antiviral Agents
Hepatitis B Surface Antigens