Abstract
Three new glycoalkaloids, N-formyl-asimilobine-2-O-β-D-glucoside (1), (-)-1-O-β-D-glucoside-8-oxotetrahydropalmatine (2), and 1-N-monomethylcarbamate-argentinine-3-O-β-D-glucoside (3) were isolated from tubers of Stephania succifera. The structures were established based on spectroscopic analysis, and the antimicrobial activities of the three glycoalkaloids are reported.
Keywords:
Alkaloid; Antimicrobial activity; Glycoalkaloid; Stephania succifera.
MeSH terms
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Alkaloids / chemistry
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Alkaloids / isolation & purification
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Alkaloids / pharmacology*
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Anti-Bacterial Agents / chemistry
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Anti-Bacterial Agents / isolation & purification
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Anti-Bacterial Agents / pharmacology*
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Candida albicans / drug effects*
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Dose-Response Relationship, Drug
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Microbial Sensitivity Tests
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Molecular Structure
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Staphylococcus aureus / drug effects*
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Stephania / chemistry*
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Structure-Activity Relationship
Substances
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Alkaloids
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Anti-Bacterial Agents