Tear menisci after laser in situ keratomileusis with mechanical microkeratome and femtosecond laser

Invest Ophthalmol Vis Sci. 2014 Aug 21;55(9):5806-12. doi: 10.1167/iovs.13-13669.

Abstract

Purpose: To investigate the effect on tear menisci after laser in situ keratomileusis (LASIK) with flap creation by either microkeratome or femtosecond laser.

Methods: Sixty eyes of 30 myopes were analyzed. Fifteen patients underwent LASIK with Moria II microkeratome, and the other 15 patients with 60-KHz IntraLase femtosecond laser. Upper and lower tear meniscus parameters of height (UTMH, LTMH) and area (UTMA, LTMA) were measured by SD-OCT preoperatively and 1 week, 1 month, and 3 months postoperatively.

Results: Compared with the baseline values, all tear meniscus parameters decreased significantly at each postoperative time point (all P < 0.01) in both groups. LTMH increased significantly between 1 week and 1 month and between 1 and 3 months after surgery in the microkeratome (both P < 0.01) and femtosecond laser groups (P < 0.01, P = 0.012, respectively). There were significant increases in LTMA between 1 week and 1 month after surgery in the microkeratome group (P < 0.01) and in the femtosecond laser group (P = 0.028). There were no significant differences in UTMH, UTMA, LTMH, or LTMA between two groups. The depth of ablation was negatively correlated with the LTMA at 1 week after surgery (R = -0.256, P = 0.049) for all patients.

Conclusions: There were no significant differences in the tear meniscus parameters between the microkeratome and femtosecond laser groups. The depth of ablation was significantly correlated with the LTMA only at 1 week after surgery.

Keywords: SD-OCT; dry eyes; laser in situ keratomileusis; tear meniscus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Analysis of Variance
  • Cornea / surgery*
  • Female
  • Humans
  • Keratomileusis, Laser In Situ / adverse effects*
  • Keratomileusis, Laser In Situ / methods
  • Lasers, Excimer
  • Male
  • Myopia / physiopathology
  • Myopia / surgery
  • Surgical Flaps
  • Tears / physiology*
  • Tomography, Optical Coherence
  • Young Adult