Electrospun polymer mat as a SERS platform for the immobilization and detection of bacteria from fluids

Analyst. 2014 Oct 21;139(20):5061-4. doi: 10.1039/c4an01137f.

Abstract

This work demonstrates the development of a new class of SERS substrates that allows for the simultaneous: (i) filtration of bacteria from any solution (blood, urine, water, or milk), (ii) immobilization of bacteria on the SERS platform, and (iii) enhancing the Raman signal of bacteria. The proposed platform is based on an electrospun polymer mat covered with a 90 nm layer of gold.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacteria / chemistry*
  • Bacteria / metabolism
  • Bacteriological Techniques / instrumentation*
  • Body Fluids / microbiology*
  • Gold / chemistry
  • Humans
  • Metal Nanoparticles / chemistry
  • Metal Nanoparticles / ultrastructure
  • Particle Size
  • Polymers / chemistry*
  • Spectrum Analysis, Raman*
  • Staphylococcus aureus / chemistry
  • Staphylococcus aureus / metabolism

Substances

  • Polymers
  • Gold