Frequency-modulated light scattering interferometry employed for optical properties and dynamics studies of turbid media

Biomed Opt Express. 2014 Jul 28;5(8):2810-22. doi: 10.1364/BOE.5.002810. eCollection 2014 Aug 1.

Abstract

In the present work, fiber-based frequency-modulated light scattering interferometry (FMLSI) is developed and employed for studies of optical properties and dynamics in liquid phantoms made from Intralipid(®). The fiber-based FMLSI system retrieves the optical properties by examining the intensity fluctuations through the turbid medium in a heterodyne detection scheme using a continuous-wave frequency-modulated coherent light source. A time resolution of 21 ps is obtained, and the experimental results for the diluted Intralipid phantoms show good agreement with the predicted results based on published data. The present system shows great potential for assessment of optical properties as well as dynamic studies in liquid phantoms, dairy products, and human tissues.

Keywords: (120.5820) Scattering measurements; (120.6160) Speckle interferometry; (290.7050) Turbid media.