Diagnostic value of bone scintigraphy for aseptic loosening after total knee arthroplasty

Technol Health Care. 2014;22(5):767-73. doi: 10.3233/THC-140850.

Abstract

Background: Despite technical improvements, aseptic loosening after total knee arthroplasty (TKA) remains a frequent complication. A one-stage revision arthroplasty is the most common therapeutic pathway.

Objective: The aim of this study was to evaluate the diagnostic value of bone scintigraphy in detecting aseptic loosening after TKA.

Methods: We retrospectively identified 46 cases of one-stage revision TKA performed between January 2011 and December 2012. In each case a bone scintigraphy was performed at least one year after the primary TKA and 3.2 ± 2.2 month prior to revision arthroplasty. Additionally, we evaluated the rate of satisfaction and pain level 16.2 ± 5.4 months after one-stage revision arthroplasty.

Results: Bone scintigraphy indicated aseptic loosening in 28 cases. Intraoperative aseptic loosening was verified in 34 cases. Bone scintigraphy had a sensitivity of 0.76 and a specificity of 0.83 in detecting aseptic loosening. The positive predictive value was 0.93, and the negative predictive value 0.56. At follow-up consultation, 35 patients were very satisfied or satisfied, and 31 patients had no pain or occasional pain.

Conclusions: Bone scintigraphy is a helpful tool in detecting aseptic loosening after TKA. Nevertheless, the results from bone scintigraphy should be compared with clinical findings and patients' disorders.

Keywords: Aseptic loosening; one-stage revision arthroplasty; total knee arthroplasty.

MeSH terms

  • Aged
  • Arthroplasty, Replacement, Knee / adverse effects*
  • Diagnosis, Differential
  • Female
  • Humans
  • Male
  • Middle Aged
  • Patient Satisfaction
  • Prosthesis Failure / adverse effects*
  • Radionuclide Imaging / methods*
  • Reoperation
  • Retrospective Studies
  • Sensitivity and Specificity