Open reconstruction of recurrent vesicourethral anastomotic stricture after radical prostatectomy

Int Urol Nephrol. 2014 Nov;46(11):2147-52. doi: 10.1007/s11255-014-0816-9. Epub 2014 Aug 19.

Abstract

Objectives: To determine the outcomes of open vesicourethral anastomotic reconstruction (VUAR) for outlet stenosis following radical prostatectomy (RP).

Methods: Review of all cases of VUAR within an IRB-approved database was performed. Preoperative factors assessed included cancer treatment modality, duration of symptoms, prior treatments, and length of defect. Outcomes reviewed included length-of-stay (LOS), complications, maintenance of patency, continence, and need for additional procedures.

Results: Twelve cases of VUAR performed by a single surgeon (BJF) from 2004 to 2012 were identified. Surgical approaches were either abdominal (7), perineal (3), or abdominoperineal (2). All patients underwent prior RP, with 25 % having subsequent radiotherapy. Among patients with stenosis, 43 % were completely obliterated. Two cases had prior anastomotic disruption in the early postoperative period after RP. The median length of stenosis was 2.5 cm (range 1-5 cm) and median LOS was 3.0 days (range 1-7 days). At a median follow-up of 75.5 months (range 14-120 months), 92 % of men retained patency; only 25 % were continent.

Conclusion: In experienced hands, VUAR can restore durable patency for men afflicted with outlet stenosis after RP. Despite anatomic restoration, incontinence is likely.

MeSH terms

  • Aged
  • Anastomosis, Surgical / adverse effects
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Plastic Surgery Procedures / methods*
  • Postoperative Complications / surgery*
  • Prostatectomy / adverse effects*
  • Prostatic Neoplasms / surgery
  • Recurrence
  • Retrospective Studies
  • Treatment Outcome
  • Urethra / surgery*
  • Urethral Stricture / etiology
  • Urethral Stricture / physiopathology
  • Urethral Stricture / surgery*
  • Urinary Bladder / surgery*
  • Urination