Prevalence of abnormal anal cytology in HIV-infected women: a hospital-based study

Asian Pac J Cancer Prev. 2014;15(15):6405-9. doi: 10.7314/apjcp.2014.15.15.6405.

Abstract

Background: To study the prevalence of abnormal anal cytology by Papanicolaou (Pap) technique in HIV- infected women who attended a HIV clinic at Prapokklao Hospital, Chanthaburi, Thailand.

Materials and methods: HIV-infected women who attended a HIV clinic at Prapokklao Hospital from March 2013 to February 2014 were recruited for anal Pap smears. Participants who had abnormal results of equally or over "abnormal squamous/glandular cells of undetermined significance" (ASC-US) were classified as abnormal anal cytology.

Results: A total of 590 anal Pap smears were performed at HIV clinic of Prapokklao Hospital during the study period. There were only 13 patients who had abnormal Pap tests, which were: 11 ASC-US and 2 HSIL (high grade squamous intraepithelial lesion). The prevalence of abnormal anal Pap smears in HIV-infected women who attended HIV clinic at Prapokklao Hospital was 2.2 percent. Percentage of high risk HPV in patients who had abnormal Pap test was 88.9 (8/9).

Conclusions: The prevalence of abnormal anal Papanicolaou smears in HIV-infected women who attended the HIV clinic at Prapokklao hospital was quite low in comparison to the earlier literature.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Anal Canal / pathology*
  • Anal Canal / virology
  • Anus Neoplasms / epidemiology*
  • Anus Neoplasms / etiology
  • Anus Neoplasms / pathology
  • Carcinoma, Squamous Cell / epidemiology*
  • Carcinoma, Squamous Cell / etiology
  • Carcinoma, Squamous Cell / pathology
  • Female
  • Follow-Up Studies
  • HIV / pathogenicity
  • HIV Infections / complications*
  • HIV Infections / pathology
  • HIV Infections / virology
  • Humans
  • Middle Aged
  • Neoplasm Staging
  • Papanicolaou Test
  • Papillomaviridae / pathogenicity
  • Papillomavirus Infections / complications
  • Papillomavirus Infections / pathology
  • Papillomavirus Infections / virology
  • Prevalence
  • Prognosis
  • Prospective Studies
  • Thailand / epidemiology
  • Uterine Cervical Dysplasia / epidemiology*
  • Uterine Cervical Dysplasia / etiology
  • Uterine Cervical Dysplasia / pathology
  • Vaginal Smears
  • Young Adult