Anhedonia in prolonged schizophrenia spectrum patients with relatively lower vs. higher levels of depression disorders: associations with deficits in social cognition and metacognition

Conscious Cogn. 2014 Oct:29:68-75. doi: 10.1016/j.concog.2014.07.005. Epub 2014 Aug 10.

Abstract

This study has sought to explore whether there are at least two subtypes of anhedonia in schizophrenia: one closely linked with depression and another that occurs in the absence of depression which is related to a general paucity of internal experience. Participants were 163 adults with schizophrenia who completed assessments of depression, anhedonia, executive functioning, positive and negative symptoms, social cognition and metacognition. A cluster analysis based on participants' depression and anhedonia symptom scores produced three groups: High Depression/High Anhedonia (n=52), Low Depression/Low Anhedonia (n=52), and Low Depression/High Anhedonia (n=59). An ANCOVA and post hoc comparisons controlling for positive and negative symptoms found that the Low Depression/High Anhedonia group had poorer metacognition and social cognition than other groups. These findings point to the possibility of a subtype of anhedonia in schizophrenia, one occurring in the relative lesser levels of depression, and tied to deficits in the ability to think about oneself and others.

Keywords: Anhedonia; Depression; Metacognition; Schizophrenia; Social cognition.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Anhedonia / physiology*
  • Cognition Disorders / epidemiology
  • Cognition Disorders / physiopathology*
  • Comorbidity
  • Depressive Disorder / epidemiology
  • Depressive Disorder / physiopathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Schizophrenia / epidemiology
  • Schizophrenia / physiopathology*
  • Social Perception*