Need for multi-scale systems to identify spindle orientation regulators relevant to tissue disorganization in solid cancers

Front Physiol. 2014 Jul 25:5:278. doi: 10.3389/fphys.2014.00278. eCollection 2014.

¹ Department of Genetics, Cancer Cell Biology, University of Cambridge Cambridge, UK.

No abstract available

Keywords: Hippo pathway; PTEN regulation; Wnt pathway; cancer inititation; cancer progression; cell division; microtubules; spindle orientation.