Clear cell myoepithelial carcinoma ex pleomorphic adenoma

Indian J Pathol Microbiol. 2014 Jul-Sep;57(3):456-9. doi: 10.4103/0377-4929.138768.

Abstract

Pleomorphic adenoma is the most common epithelial neoplasm of lacrimal gland. A clear cell myoepithelial carcinoma arising in the background of pleomorphic adenoma is common in the salivary glands but very rare in the lacrimal glands. We report the case of a 27 year old man whose lacrimal gland pleomorphic adenoma recurred several times over a period of four years and ultimately evolved into a clear cell myoepithelial carcinoma ex pleomorphic adenoma.

Publication types

  • Case Reports

MeSH terms

  • Adenoma, Pleomorphic / complications*
  • Adult
  • Biomarkers, Tumor / analysis
  • Calcium-Binding Proteins / analysis
  • Calponins
  • Carcinoma / diagnosis*
  • Carcinoma / pathology*
  • Head / diagnostic imaging
  • Histocytochemistry
  • Humans
  • Immunohistochemistry
  • Lacrimal Apparatus / pathology*
  • Magnetic Resonance Imaging
  • Male
  • Microfilament Proteins / analysis
  • Microscopy
  • Mucin-1 / analysis
  • Myoepithelioma / diagnosis*
  • Myoepithelioma / pathology*
  • Radiography

Substances

  • Biomarkers, Tumor
  • Calcium-Binding Proteins
  • Microfilament Proteins
  • Mucin-1