Successful RAG1-SCID gene therapy depends on the level of RAG1 expression

Affiliations

• ¹ Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands.
• ² Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany.
• ³ Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands.
• ⁴ Département de Biothérapie, Hôpital Necker-Enfants Malades, Paris, France.
• ⁵ Department of Pediatrics, Erasmus Medical Center, Rotterdam, The Netherlands.
• ⁶ Molecular Immunology Unit, UCL Institute of Child Health, London, United Kingdom.
• ⁷ Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands.
• ⁸ Department of Pharmacy, Leiden University Medical Center, Leiden, The Netherlands.
• ⁹ Department of Immunology, Erasmus Medical Center, Rotterdam, The Netherlands.
• ¹⁰ Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands. Electronic address: f.j.t.staal@lumc.nl.