Abstract
Two new cyclic dipeptides, rhinocladin A (1) and rhinocladin B (2), were isolated from a fungal endophyte (Rhinocladiella sp. lgt-3) of Tripterygium wilfordii Hook. Their structures were elucidated by 1D and 2D NMR spectra. The monoamine oxidase inhibitory activity of 1 and 2 was also evaluated.
Keywords:
Rhinocladiella; Tripterygiun wilfordii; cyclic dipeptides; endophyte; monoamine oxidase inhibitors.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Dipeptides / chemistry*
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Dipeptides / isolation & purification
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Endophytes / chemistry
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Magnetic Resonance Spectroscopy
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Mitosporic Fungi / chemistry*
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Molecular Structure
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Monoamine Oxidase Inhibitors / chemistry
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Monoamine Oxidase Inhibitors / isolation & purification
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Peptides, Cyclic / chemistry*
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Peptides, Cyclic / isolation & purification
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Tripterygium / microbiology*
Substances
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Dipeptides
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Monoamine Oxidase Inhibitors
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Peptides, Cyclic
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rhinocladin A
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rhinocladin B