Pitavastatin decreases serum LOX-1 ligand levels and MT1-MMP expression in CD14-positive mononuclear cells in hypercholesterolemic patients

Int J Cardiol. 2014 Oct 20;176(3):1230-2. doi: 10.1016/j.ijcard.2014.07.213. Epub 2014 Aug 4.
No abstract available

Keywords: LOX-1 ligand; MT1-MMP; Pitavastatin; Plaque vulnerability.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Humans
  • Hydroxymethylglutaryl-CoA Reductase Inhibitors / therapeutic use
  • Hypercholesterolemia / blood
  • Hypercholesterolemia / drug therapy*
  • Hypercholesterolemia / immunology
  • Leukocytes, Mononuclear / immunology*
  • Ligands
  • Lipopolysaccharide Receptors / immunology*
  • Male
  • Matrix Metalloproteinase 14 / biosynthesis*
  • Middle Aged
  • Quinolines / therapeutic use*
  • Scavenger Receptors, Class E / blood*

Substances

  • Hydroxymethylglutaryl-CoA Reductase Inhibitors
  • Ligands
  • Lipopolysaccharide Receptors
  • OLR1 protein, human
  • Quinolines
  • Scavenger Receptors, Class E
  • MMP14 protein, human
  • Matrix Metalloproteinase 14
  • pitavastatin