Enzyme immobilised novel core-shell superparamagnetic nanocomposites for enantioselective formation of 4-(R)-hydroxycyclopent-2-en-1-(S)-acetate

Chem Commun (Camb). 2014 Oct 4;50(76):11185-7. doi: 10.1039/c4cc05358c.

Abstract

Lipase immobilized novel high surface area core-shell superparamagnetic nanoparticles have been fabricated and used as efficient reusable catalysts for the selective production of pharmaceutically important chiral isomers from meso-cyclopent-2-en-1,4-diacetate.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acetates / chemistry
  • Acetates / metabolism*
  • Biocatalysis
  • Cyclopentanes / chemistry
  • Cyclopentanes / metabolism*
  • Enzymes, Immobilized / chemistry
  • Enzymes, Immobilized / metabolism*
  • Lipase / chemistry
  • Lipase / metabolism*
  • Magnetite Nanoparticles / chemistry*
  • Molecular Conformation
  • Particle Size
  • Stereoisomerism

Substances

  • Acetates
  • Cyclopentanes
  • Enzymes, Immobilized
  • Magnetite Nanoparticles
  • Lipase