Abstract
Hydroxyapatite (HA), the main mineral component of bones and teeth, was synthesized by using the reaction between calcium nitrate tetrahydrate Ca(NO3)2∙4H2O and diammonium hydrogen phosphate (NH4)2HPO4 (DAHP) with a chemical precipitation method. The objective of this study is to utilize novel inorganic-organic nanocomposites for biomedical applications. HA is an inorganic component (75% w) and chitosan, alginate and albumin (Egg white) are organic components of nanocomposites (25% w). Nanocomposites were prepared in deionized water solutions, at room temperature, using a mechanical and magnetic stirrer for 48 h. The microstructure and morphology of sintered n-HAP were tested at different preheating temperature and laser sintering speed with scanning electron microscopy (SEM), X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FT-IR).
Keywords:
biomedical applications; hydroxyapatite; inorganic–organic nanocomposite; natural polymers.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Albumins / chemistry
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Albumins / pharmacology
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Alginates / chemistry
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Alginates / pharmacology
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Biocompatible Materials / chemical synthesis*
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Biocompatible Materials / pharmacology
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Calcium Compounds / chemistry
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Cell Line, Tumor
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Cell Survival / drug effects
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Chemical Precipitation
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Chitosan / chemistry
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Chitosan / pharmacology
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Dental Materials / chemical synthesis*
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Dental Materials / pharmacology
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Durapatite / chemical synthesis*
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Durapatite / pharmacology
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Fibroblasts / cytology
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Fibroblasts / drug effects
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Glucuronic Acid / chemistry
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Glucuronic Acid / pharmacology
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Hexuronic Acids / chemistry
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Hexuronic Acids / pharmacology
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Humans
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Materials Testing
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Microscopy, Electron, Scanning
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Nanocomposites / chemistry*
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Nanocomposites / ultrastructure
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Nitrates / chemistry
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Phosphates / chemistry
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Spectroscopy, Fourier Transform Infrared
Substances
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Albumins
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Alginates
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Biocompatible Materials
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Calcium Compounds
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Dental Materials
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Hexuronic Acids
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Nitrates
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Phosphates
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ammonium phosphate
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Glucuronic Acid
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Chitosan
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Durapatite
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calcium nitrate