Diagnosis and treatment of endocrine comorbidities in patients with cystic fibrosis

Curr Opin Endocrinol Diabetes Obes. 2014 Oct;21(5):422-9. doi: 10.1097/MED.0000000000000096.

Abstract

Purpose of review: The aim of this review is to provide an update on various relevant endocrine aspects of care in adolescents and adults with cystic fibrosis.

Recent findings: As life expectancy in cystic fibrosis has continuously improved, endocrine complications have become more apparent. The common endocrine complications include cystic fibrosis related diabetes, cystic fibrosis related bone disease, vitamin D deficiency and poor growth and pubertal development. Thyroid and adrenal disorders have also been reported, although the prevalence appears to be less common.

Summary: Endocrine diseases are an increasingly recognized complication that has a significant impact on the overall health of individuals with cystic fibrosis. This review summarizes the updated screening and management of endocrine diseases in the cystic fibrosis population.

Publication types

  • Review

MeSH terms

  • Absorptiometry, Photon
  • Body Height
  • Bone Diseases, Endocrine / diagnosis*
  • Bone Diseases, Endocrine / epidemiology
  • Bone Diseases, Endocrine / therapy
  • Comorbidity
  • Cystic Fibrosis / complications*
  • Cystic Fibrosis / epidemiology
  • Cystic Fibrosis / therapy
  • Diabetes Mellitus / diagnosis*
  • Diabetes Mellitus / epidemiology
  • Diabetes Mellitus / therapy
  • Female
  • Glycated Hemoglobin / metabolism
  • Growth Disorders / diagnosis*
  • Growth Disorders / epidemiology
  • Growth Disorders / therapy
  • Humans
  • Male
  • Mass Screening / methods
  • Nutritional Status
  • Prevalence
  • Thyroid Diseases / diagnosis*
  • Thyroid Diseases / epidemiology
  • Thyroid Diseases / therapy
  • Vitamin D Deficiency / diagnosis*
  • Vitamin D Deficiency / epidemiology
  • Vitamin D Deficiency / therapy

Substances

  • Glycated Hemoglobin A
  • hemoglobin A1c protein, human