Review of choroidal osteomas

Middle East Afr J Ophthalmol. 2014 Jul-Sep;21(3):244-50. doi: 10.4103/0974-9233.134686.

Abstract

Choroidal osteomas are rare benign ossifying tumors that appear as irregular slightly elevated, yellow-white, juxtapapillary, choroidal mass with well-defined geographic borders, depigmentation of the overlying pigment epithelium; and with multiple small vascular networks on the tumor surface. Visual loss results from three mechanisms: Atrophy of the retinal pigment epithelium overlying a decalcified osteoma; serous retinal detachment over the osteoma from decompensated retinal pigment epithelium, and most commonly from choroidal neovascularization. Recent evidence points to the beneficial effects of intravitreal vascular endothelial growth factor antagonists in improving visual acuity in serous retinal detachment with or without choroidal neovascularization.

Keywords: Argon Laser; Choroidal Osteoma; Intravitreal Bevacizumab; Intravitreal Ranibizumab; Photodynamic Therapy.

Publication types

  • Review

MeSH terms

  • Calcinosis / physiopathology
  • Choristoma* / etiology
  • Choristoma* / pathology
  • Choristoma* / physiopathology
  • Choroid Neoplasms* / etiology
  • Choroid Neoplasms* / pathology
  • Choroid Neoplasms* / physiopathology
  • Humans
  • Osteoma* / etiology
  • Osteoma* / pathology
  • Osteoma* / physiopathology

Supplementary concepts

  • Choroidal Osteoma, Bilateral