Justidrusamides A-D, new 2-aminobenzyl alcohol derivatives from Justicia gendarussa

Yuko Kiren; Jun Deguchi; Yusuke Hirasawa; Hiroshi Morita; Bambang Prajogo

doi:10.1007/s11418-014-0862-8

Justidrusamides A-D, new 2-aminobenzyl alcohol derivatives from Justicia gendarussa

J Nat Med. 2014 Oct;68(4):754-8. doi: 10.1007/s11418-014-0862-8. Epub 2014 Aug 7.

Authors

Yuko Kiren¹, Jun Deguchi, Yusuke Hirasawa, Hiroshi Morita, Bambang Prajogo

Affiliation

¹ Faculty of Pharmaceutical Sciences, Hoshi University, Ebara 2-4-41 Shinagawa-ku, Tokyo, 142-8501, Japan.

PMID: 25099953
DOI: 10.1007/s11418-014-0862-8

Abstract

Justidrusamides A-D (1-4), four new alkaloids containing 2-aminobenzyl alcohol, succinic acid, and 2,3-dihydroxy-2-(1-hydroxyethyl) butanoic acid skeletons have been isolated from leaves of Justicia gendarussa, and their structures were elucidated using 2D NMR data and chemical means. This is the first report of a 2,3-dihydroxy-2-(1-hydroxyethyl) butanoic acid derivative in nature.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Acanthaceae / chemistry*
Alkaloids / chemistry*
Benzyl Alcohols / chemistry*
Plant Leaves / chemistry

Substances

Alkaloids
Benzyl Alcohols
2-aminobenzyl alcohol