The role of bridge therapy prior to orthotopic liver transplantation

J Natl Compr Canc Netw. 2014 Aug;12(8):1183-90; quiz 1191. doi: 10.6004/jnccn.2014.0113.

Abstract

Orthotopic liver transplantation (OLT) offers the best chance for cure in the setting of unresectable hepatocellular carcinoma (HCC). A consensus statement recommends locoregional therapy (LRT) be considered in patients with HCC who are expected to wait more than 6 months for OLT to diminish dropout from the waiting list because of tumor progression. This article reviews LRT as a bridge to OLT in patients with HCC.

Publication types

  • Review

MeSH terms

  • Carcinoma, Hepatocellular / metabolism
  • Carcinoma, Hepatocellular / pathology
  • Carcinoma, Hepatocellular / therapy*
  • Embolization, Therapeutic
  • Humans
  • Liver Neoplasms / pathology
  • Liver Neoplasms / therapy*
  • Liver Transplantation*
  • Patient Dropouts
  • Retrospective Studies
  • alpha-Fetoproteins / metabolism

Substances

  • alpha-Fetoproteins