Bone health in children with neuromuscular disorders

J Pediatr Rehabil Med. 2014;7(2):133-42. doi: 10.3233/PRM-140282.

Abstract

This paper provides a broad review of bone health issues in children with neuromuscular diseases (NMD). As Duchenne muscular dystrophy is the most common neuromuscular disease of childhood, there is a strong emphasis on this. This paper reviews the incidence of fractures, the degree of the reduced bone mineral density, the risk factors associated with this common problem, and the non-pharmacological and pharmacological treatment options. Recommendations for monitoring and treatment are provided.

Keywords: Duchenne; Neuromuscular; fracture; spinal muscular atrophy.

Publication types

  • Review

MeSH terms

  • Absorptiometry, Photon
  • Bone Density
  • Child
  • Female
  • Fractures, Bone / etiology*
  • Fractures, Bone / prevention & control
  • Fractures, Bone / therapy*
  • Humans
  • Male
  • Muscular Dystrophy, Duchenne / complications*
  • Osteoporosis / etiology*
  • Osteoporosis / prevention & control
  • Osteoporosis / therapy*
  • Risk Factors
  • Sex Factors
  • Spinal Muscular Atrophies of Childhood / complications*