Nanopharmacology in translational hematology and oncology

Int J Nanomedicine. 2014 Jul 22:9:3465-79. doi: 10.2147/IJN.S60488. eCollection 2014.

Abstract

Nanoparticles have displayed considerable promise for safely delivering therapeutic agents with miscellaneous therapeutic properties. Current progress in nanotechnology has put forward, in the last few years, several therapeutic strategies that could be integrated into clinical use by using constructs for molecular diagnosis, disease detection, cytostatic drug delivery, and nanoscale immunotherapy. In the hope of bringing the concept of nanopharmacology toward a viable and feasible clinical reality in a cancer center, the present report attempts to present the grounds for the use of cell-free nanoscale structures for molecular therapy in experimental hematology and oncology.

Keywords: hematological malignancies; nanoparticles; translational medicine.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Drug Carriers*
  • Hematology
  • Humans
  • Mice
  • Nanomedicine*
  • Nanoparticles*
  • Neoplasms / drug therapy*
  • Translational Research, Biomedical*

Substances

  • Drug Carriers