Acute coronary syndromes: unstable angina and non-ST elevation myocardial infarction

Cardiol Clin. 2014 Aug;32(3):353-70. doi: 10.1016/j.ccl.2014.04.010.

Abstract

Non-ST elevation acute coronary syndromes (NSTE-ACS) encompass the clinical entities of unstable angina and non-ST elevation myocardial infarction. Several advances have occurred over the past decade, including the emergence of new antiplatelet and antithrombotic therapies and novel treatment strategies, leading to marked improvements in mortality. However, there has also been an increased incidence in NSTE-ACS as a result of the use of high-sensitivity troponins and the increase in cardiovascular risk factors. This article provides a focused update on contemporary management strategies pertaining to antiplatelet, antithrombotic, and anti-ischemic therapies and to revascularization strategies in patients with ACS.

Keywords: Acute coronary syndromes; Antiplatelet; Antithrombotic; Management; Non–ST elevation MI; Revascularization; Unstable angina.

Publication types

  • Review

MeSH terms

  • Acute Coronary Syndrome* / epidemiology
  • Acute Coronary Syndrome* / etiology
  • Acute Coronary Syndrome* / therapy
  • Angina, Unstable* / complications
  • Angina, Unstable* / epidemiology
  • Angina, Unstable* / therapy
  • Electrocardiography*
  • Global Health
  • Humans
  • Incidence
  • Myocardial Infarction* / complications
  • Myocardial Infarction* / epidemiology
  • Myocardial Infarction* / therapy
  • Risk Assessment*
  • Risk Factors
  • Survival Rate / trends