Supramolecular pyridyl urea gels as soft matter with antibacterial properties against MRSA and/or E. coli

Chem Commun (Camb). 2014 Sep 25;50(74):10819-22. doi: 10.1039/c4cc04028g.

Abstract

The synthesis and characterisation of novel aryl-pyridyl ureas are described, which form self-assembly structures via extended hydrogen bonding and π-π interactions in the solid state, and in selected cases, form supramolecular gels with antimicrobial properties against Staphylococcus aureus and/or Escherichia coli.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology
  • Disk Diffusion Antimicrobial Tests
  • Escherichia coli / drug effects*
  • Gels / chemistry*
  • Gels / pharmacology*
  • Hydrogen Bonding
  • Methicillin-Resistant Staphylococcus aureus / drug effects*
  • Pyridines / chemistry*
  • Urea / chemistry*
  • Urea / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Gels
  • Pyridines
  • Urea
  • pyridine