Carinatines A and B, Lycopodium Alkaloids from Phlegmariurus carinatus

Nat Prod Bioprospect. 2014 Aug;4(4):221-5. doi: 10.1007/s13659-014-0030-6. Epub 2014 Jul 17.

Abstract

Carinatine A (1), a C16N2-type Lycopodium alkaloid possessing a 5/6/6/6 ring system formed by a new C-4/C-12 bond, and carinatine B (2), the first derivative of lycojaponicumin C, along 16 known compounds, were isolated from the whole plant of Phlegmariurus carinatus. Their structures were elucidated based on the spectroscopic data. The two new isolates were no inhibitory activity for the acetylcholinesterase (AChE).

Keywords: Acetylcholinesterase (AChE) inhibitory activity; Carinatines A and B; Lycopodium alkaloid; Phlegmariurus carinatus.