The intractable intra-abdominal hemorrhage with unknown etiology in a patient with severe hemophilia A

Am J Emerg Med. 2015 Jan;33(1):129.e1-3. doi: 10.1016/j.ajem.2014.06.038. Epub 2014 Jul 1.

Abstract

Severe hemophilia patients are more likely to be complicated by intra-articular hemorrhage, subcutaneous hemorrhage, and intra-mascular hemorrhage. Spontaneous intra-abdominal hemorrhage is a rare fatal disease, which is an arterial bleeding of uncertain causes from vessel feeding arteries. In case the spontaneous intra-abdominal hemorrhage is complicated to severe hemophilia patients, the mortality rate increases considerably. We experienced a patient with severe hemophilia A, who made a full recovery from spontaneous intra-abdominal hemorrhagic shock by replacement therapy of coagulation factor VII, a noninvasive procedure.

Publication types

  • Case Reports

MeSH terms

  • Angiography
  • Diagnosis, Differential
  • Factor VIIa / therapeutic use
  • Hemoperitoneum / diagnosis*
  • Hemoperitoneum / drug therapy
  • Hemophilia A / complications*
  • Humans
  • Male
  • Middle Aged
  • Recombinant Proteins / therapeutic use
  • Tomography, X-Ray Computed

Substances

  • Recombinant Proteins
  • recombinant FVIIa
  • Factor VIIa