Implications of vitamin D deficiency in lithiasic patient and in general population

Abstract

Context and objective: Vitamin D deficiency causes problems in mineral metabolism but also overall health. In first place a review of the topic was carried out. Then, in order to contextualize it in lithiasic patient, a study on Vitamin D deficiency and its possible relationship with impaired PTH levels is performed.

Evidences acquisition: A review of topics such as metabolism, epidemiology and the relationship of vitamin D deficiency with several pathologies was performed. Besides a multivariate analysis and a correlation study between vitamin D and PTH levels was conducted in 100 lithiasic patients.

Evidences synthesis: We present a review of Vitamin D metabolism, receptors and functions, as well as about its valuation methodology and the treatment of its deficiency. Lithiasic patients show a higher vitamin D deficiency than general population. Vitamin D deficiency has been significantly associated with increased PTH levels. In addition, there is enough literature showing a relationship between vitamin D deficiency not only with bone disease, but also with multiple diseases.

Conclusion: vitamin D levels should be measured in all lithiasic patients, and those with vitamin D deficiency should be treated.

Keywords: Hormona paratiroidea; Litiasis urinaria; Metabolismo fosfocálcico; Parathyroid hormone; Phosphocalcic metabolism; Urinary lithiasis; Vitamin D; Vitamina D.