Endoscopic submucosal tunnel dissection salvage technique for ulcerative early gastric cancer

World J Gastroenterol. 2014 Jul 21;20(27):9210-4. doi: 10.3748/wjg.v20.i27.9210.

Abstract

Endoscopic submucosal dissection is an effective treatment modality for early gastric cancer (EGC), though the submucosal fibrosis found in ulcerative EGC is an obstacle for successful treatment. This report presents two cases of ulcerative EGC in two males, 73- and 80-year-old, with severe fibrosis. As endoscopic ultrasonography suggested that the EGCs had invaded the submucosal layer, the endoscopic submucosal tunnel dissection salvage technique was utilized for complete resection of the lesions. Although surgical gastrectomy was originally scheduled, the two patients had severe coronary heart disease, and surgeries were refused because of the risks associated with their heart conditions. The endoscopic submucosal tunnel dissection salvage technique procedures described in these cases were performed under conscious sedation, and were completed within 30 min. The complete en bloc resection of EGC using endoscopic submucosal tunnel dissection salvage technique was possible with a free resection margin, and no other complications were noted during the procedure. This is the first known report concerning the use of the endoscopic submucosal tunnel dissection salvage technique salvage technique for treatment of ulcerative EGC. We demonstrate that endoscopic submucosal tunnel dissection salvage technique it is a feasible method showing several advantages over endoscopic submucosal dissection for cases of EGC with fibrosis.

Keywords: Early gastric cancer; Endoscopic submucosal dissection; Endoscopic submucosal tunnel dissection; Endoscopy; Fibrosis.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biopsy
  • Conscious Sedation
  • Coronary Disease / complications
  • Dissection / methods*
  • Endosonography
  • Fibrosis
  • Gastrectomy / methods*
  • Gastric Mucosa / diagnostic imaging
  • Gastric Mucosa / pathology
  • Gastric Mucosa / surgery*
  • Gastroscopy / methods*
  • Humans
  • Male
  • Neoplasm Invasiveness
  • Stomach Neoplasms / complications
  • Stomach Neoplasms / diagnostic imaging
  • Stomach Neoplasms / pathology
  • Stomach Neoplasms / surgery*
  • Stomach Ulcer / complications
  • Stomach Ulcer / diagnostic imaging
  • Stomach Ulcer / pathology
  • Stomach Ulcer / surgery*
  • Treatment Outcome