Controlling lipid membrane architecture for tunable nanoplasmonic biosensing

Small. 2014 Dec 10;10(23):4828-32. doi: 10.1002/smll.201400518. Epub 2014 Jul 30.

Abstract

Tunable nanoplasmonic biosensing for lipid and protein applications is reported based on controlling lipid membrane architecture on surfaces. The interaction of a peptide with lipid membranes is highly sensitive to the membrane architecture on top of plasmonic nanodisks, and the measurement response varies in a manner which is consistent with the surrounding lipid environment.

Keywords: biomimetics; biosensors; nanotechnology; self-assembly; tunable plasmonic properties.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adsorption
  • Biosensing Techniques*
  • Glass
  • Gold / chemistry*
  • Lipids / chemistry*
  • Membranes, Artificial
  • Metal Nanoparticles / chemistry*
  • Microscopy, Atomic Force
  • Nanostructures
  • Nanotechnology / methods
  • Peptides / chemistry
  • Silicon Dioxide / chemistry
  • Surface Plasmon Resonance

Substances

  • Lipids
  • Membranes, Artificial
  • Peptides
  • Gold
  • Silicon Dioxide