Attachment anxiety predicts IL-6 and length of hospital stay in coronary artery bypass graft surgery (CABG) patients

J Psychosom Res. 2014 Aug;77(2):155-7. doi: 10.1016/j.jpsychores.2014.06.002. Epub 2014 Jun 13.

Abstract

Objective: The mechanisms underlying the association between adult attachment and health are not well understood. In the current study, we investigated the relationship between attachment anxiety, attachment avoidance, inflammation, and length of hospital stay in coronary artery bypass graft (CABG) surgery patients.

Method: 167 CABG patients completed an attachment questionnaire prior to surgery, and blood samples were taken before and after surgery to assess inflammatory activity.

Results: We found that attachment anxiety predicted higher plasma interleukin 6 (IL-6) concentration, and this association was mediated by self-reported sleep quality. Anxious attachment also predicted longer hospital stays following CABG surgery, even after controlling for demographic and clinical factors.

Conclusion: These data suggest that increased levels of IL-6 may be a process linking adult attachment anxiety with health outcomes.

Keywords: Attachment; CABG; Hospital stay; IL-6; Sleep.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Anxiety* / blood
  • Anxiety* / diagnosis
  • Anxiety* / etiology
  • Biomarkers / blood
  • Coronary Artery Bypass*
  • Female
  • Humans
  • Inflammation / blood*
  • Interleukin-6 / blood*
  • Length of Stay*
  • Male
  • Middle Aged
  • Object Attachment*
  • United Kingdom

Substances

  • Biomarkers
  • Interleukin-6