Effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers

Rev Soc Bras Med Trop. 2014 May-Jun;47(3):389-91. doi: 10.1590/0037-8682-0137-2013.

Abstract

Introduction: The aim of this study was to investigate the effects of Rosmarinus officinalis essential oil on germ tube formation by Candida albicans isolated from denture wearers.

Methods: Ten C. albicans isolates recovered from denture wearers were tested using 10% fetal bovine serum with or without 4% R. officinalis essential oil.

Results: The essential oil from R. officinalis completely inhibited germ tube formation in the investigated C. albicans isolates.

Conclusions: The results demonstrate that the essential oil of R. officinalis modulates C. albicans pathogenicity through its primary virulence factor (i.e., germ tube formation was suppressed).

MeSH terms

  • Aged
  • Antifungal Agents / isolation & purification
  • Antifungal Agents / pharmacology*
  • Candida albicans / drug effects*
  • Candida albicans / isolation & purification
  • Dentures / microbiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Oils, Volatile / pharmacology*
  • Rosmarinus / chemistry*

Substances

  • Antifungal Agents
  • Oils, Volatile