Meta-analysis shows that infants who have suffered neonatal sepsis face an increased risk of mortality and severe complications

Acta Paediatr. 2014 Dec;103(12):1211-8. doi: 10.1111/apa.12764. Epub 2014 Sep 7.

Abstract

Infants suffering from neonatal sepsis face an increased risk of early death and long-term neurodevelopmental delay. This paper analyses and summarises the existing data on short-term and long-term outcomes of neonatal sepsis, based on 12 studies published between January 2000 and 1 April 2012 and covering 3669 neonates with sepsis.

Conclusion: Infants who have suffered neonatal sepsis face an increased risk of mortality and severe complications such as brain damage and, or, neurodevelopmental delay.

Keywords: Morbidity; Mortality; Neonatal sepsis; Outcome; Prognosis.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Brain Damage, Chronic / epidemiology
  • Developmental Disabilities / epidemiology
  • Humans
  • Infant
  • Infant, Newborn
  • Sepsis / mortality*