Portal vein thrombosis with protein C-S deficiency in a non-cirrhotic patient

Gustavo A Rodríguez-Leal; Segundo Morán; Roberto Corona-Cedillo; Rocío Brom-Valladares

doi:10.4254/wjh.v6.i7.532

Portal vein thrombosis with protein C-S deficiency in a non-cirrhotic patient

World J Hepatol. 2014 Jul 27;6(7):532-7. doi: 10.4254/wjh.v6.i7.532.

Authors

Gustavo A Rodríguez-Leal¹, Segundo Morán¹, Roberto Corona-Cedillo¹, Rocío Brom-Valladares¹

Affiliation

¹ Gustavo A Rodríguez-Leal, Segundo Morán, Laboratory of Gastrohepatology Research, Hospital de Pediatría, CMN Siglo XXI, Mexican Institute of Social Security, Delegación Cuauhtémoc, CP 06720, México.

Abstract

There are several conditions that can lead to portal vein thrombosis (PVT), including including infection, malignancies, and coagulation disorders. Anew condition of interest is protein C and S deficiencies, associated with hypercoagulation and recurrent venous thromboembolism. We report the case of a non-cirrhotic 63-year-old male diagnosed with acute superior mesenteric vein thrombosis and PVT and combined deficiencies in proteins C and S, recanalized by short-term low molecular heparin plus oral warfarin therapy.

Keywords: Anticoagulant therapy; Mesenteric venous thrombosis; Portal vein thrombosis; Protein C and S deficiency; Transient elastography.

Publication types

Case Reports