Regulation of cry gene expression in Bacillus thuringiensis

Toxins (Basel). 2014 Jul 23;6(7):2194-209. doi: 10.3390/toxins6072194.

Abstract

Bacillus thuringiensis differs from the closely related Bacillus cereus group species by its ability to produce crystalline inclusions. The production of these crystals mainly results from the expression of the cry genes, from the stability of their transcripts and from the synthesis, accumulation and crystallization of large amounts of insecticidal Cry proteins. This process normally coincides with sporulation and is regulated by various factors operating at the transcriptional, post-transcriptional, metabolic and post-translational levels.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Bacillus thuringiensis / genetics*
  • Bacillus thuringiensis / metabolism
  • Bacterial Proteins / chemistry
  • Bacterial Proteins / genetics*
  • Bacterial Proteins / metabolism
  • Crystallization
  • Endotoxins / chemistry
  • Endotoxins / genetics*
  • Endotoxins / metabolism
  • Gene Expression Regulation, Bacterial*
  • Genes, Bacterial
  • Hemolysin Proteins / chemistry
  • Hemolysin Proteins / genetics*
  • Hemolysin Proteins / metabolism
  • RNA, Messenger / genetics

Substances

  • Bacterial Proteins
  • Endotoxins
  • Hemolysin Proteins
  • RNA, Messenger