Effects of atmospheric pollutants (CO, O3, SO2) on the allergenicity of Betula pendula, Ostrya carpinifolia, and Carpinus betulus pollen

Int J Environ Health Res. 2015;25(3):312-21. doi: 10.1080/09603123.2014.938031. Epub 2014 Jul 24.

Abstract

Pollen of Betula pendula, Ostrya carpinifolia, and Carpinus betulus was exposed in vitro to relatively low levels of the air pollutants, namely carbon monoxide, ozone, and sulfur dioxide. The allergenicity of the exposed pollen was compared with that of non-exposed pollen samples to assess if air pollution exposition affects the allergenicity potential of pollen. The immunodetection assays indicated higher IgE recognition by all sera of allergic patients to the pollen protein extracts in all exposed samples in comparison to the non-exposed samples. These results show that the pollen exposition to low pollutants' levels induces increased allergic reaction to sensitized individuals.

Keywords: Betula pendula pollen; Carpinus betulus pollen; Ostrya carpinifolia pollen; air pollutants; allergic sensitization; pollen allergy.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Air Pollutants / pharmacology
  • Animals
  • Betula / drug effects
  • Betula / immunology
  • Betulaceae / drug effects
  • Betulaceae / immunology*
  • Carbon Monoxide / pharmacology*
  • Electrophoresis, Polyacrylamide Gel
  • Humans
  • Immune Sera
  • Immunoglobulin E / immunology
  • Immunoglobulin E / metabolism
  • Mice
  • Ozone / pharmacology*
  • Plant Proteins / analysis
  • Plant Proteins / immunology
  • Pollen / drug effects
  • Pollen / immunology*
  • Rhinitis, Allergic, Seasonal / immunology*
  • Sulfur Dioxide / pharmacology*

Substances

  • Air Pollutants
  • Immune Sera
  • Plant Proteins
  • Sulfur Dioxide
  • Immunoglobulin E
  • Ozone
  • Carbon Monoxide