PDK1: a new therapeutic target for glioblastoma?

CNS Oncol. 2014 May;3(3):177-9. doi: 10.2217/cns.14.13.

Authors

Kiran Kumar Velpula¹, Andrew J Tsung

Affiliation

¹ Departments of Cancer Biology & Pharmacology, Peoria, IL 61605, USA.

No abstract available

Publication types

Editorial
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Central Nervous System Neoplasms / enzymology*
Central Nervous System Neoplasms / therapy*
Glioblastoma / enzymology*
Glioblastoma / therapy*
Glucose / metabolism
Humans
Mitochondria / enzymology
Molecular Targeted Therapy
Protein Kinase Inhibitors / pharmacology
Protein Kinase Inhibitors / therapeutic use
Protein Serine-Threonine Kinases / antagonists & inhibitors
Protein Serine-Threonine Kinases / metabolism*
Pyruvate Dehydrogenase Acetyl-Transferring Kinase

Substances

PDK1 protein, human
Protein Kinase Inhibitors
Pyruvate Dehydrogenase Acetyl-Transferring Kinase
Protein Serine-Threonine Kinases
Glucose