mTOR: a new therapeutic target for pediatric low-grade glioma?

CNS Oncol. 2014 Mar;3(2):89-91. doi: 10.2217/cns.14.4.
No abstract available

Keywords: mTOR; neurofibromatosis; optic nerve; pediatric glioma; pilocytic astrocytoma.

Publication types

  • Editorial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Brain Neoplasms / drug therapy*
  • Brain Neoplasms / genetics
  • Brain Neoplasms / metabolism*
  • Brain Neoplasms / pathology
  • Child
  • Glioma / drug therapy*
  • Glioma / genetics
  • Glioma / metabolism*
  • Glioma / pathology
  • Humans
  • Neoplasm Grading
  • Phosphatidylinositol 3-Kinases / metabolism
  • Signal Transduction / drug effects
  • TOR Serine-Threonine Kinases / antagonists & inhibitors
  • TOR Serine-Threonine Kinases / genetics
  • TOR Serine-Threonine Kinases / metabolism*

Substances

  • MTOR protein, human
  • TOR Serine-Threonine Kinases