Docking interactions: cell-cycle regulation and beyond

Mardo Kõivomägi; Jan M Skotheim

doi:10.1016/j.cub.2014.05.060

Docking interactions: cell-cycle regulation and beyond

Curr Biol. 2014 Jul 21;24(14):R647-R649. doi: 10.1016/j.cub.2014.05.060.

Authors

Mardo Kõivomägi¹, Jan M Skotheim²

Affiliations

¹ Department of Biology, Stanford University, Stanford, CA 94305, USA.
² Department of Biology, Stanford University, Stanford, CA 94305, USA. Electronic address: Skotheim@stanford.edu.

Abstract

In budding yeast, the mating pathway activates Far1 to inhibit G1 cyclins in complex with the cyclin-dependent kinase (Cln-Cdk). Yet, the molecular mechanism has remained largely unclear for over 20 years. A recent report helps shed light on this regulation.

Publication types

Comment

MeSH terms

Cyclin-Dependent Kinase Inhibitor Proteins / genetics*
G1 Phase*
Gene Expression Regulation, Fungal*
Saccharomyces cerevisiae / genetics*
Saccharomyces cerevisiae Proteins / genetics*
Signal Transduction*

Substances

Cyclin-Dependent Kinase Inhibitor Proteins
Saccharomyces cerevisiae Proteins

Abstract

Publication types

MeSH terms

Substances

Grants and funding