Abstract
Organic field-effect transistor (OFET) sensors can meet the need for portable and real-time diagnostics. An electronicreadout enzyme-linked immunosorbent assay using OFETs for the detection of a panel of three biomarkers in complex media to create a pre-eclampsia prognostic is demonstrated, along with biodetection utilizing a fully inkjet-printed and flexible OFET to underscore our ability to produce disposable devices.
Keywords:
biodetection; organic field-effect transistors; preeclampsia; serum.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Antibodies / immunology
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Biomarkers / blood
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Enzyme-Linked Immunosorbent Assay
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Enzymes, Immobilized / chemistry
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Enzymes, Immobilized / metabolism
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Female
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Glucose Oxidase / chemistry
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Glucose Oxidase / metabolism
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Humans
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Pre-Eclampsia / diagnosis*
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Pre-Eclampsia / metabolism
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Pregnancy
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Prognosis
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Transistors, Electronic*
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Vascular Endothelial Growth Factor Receptor-1 / blood
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Vascular Endothelial Growth Factor Receptor-1 / immunology
Substances
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Antibodies
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Biomarkers
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Enzymes, Immobilized
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Glucose Oxidase
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Vascular Endothelial Growth Factor Receptor-1