Paraplegia caused by local spinal cord ischemia. An animal spinal cord ischemia model

Chin Med J (Engl). 1989 Jan;102(1):28-33.

Abstract

Local spinal cord ischemia model was established in 11 adult dogs. The anterior spinal artery, posterior spinal artery and radicular artery were cauterized with bipolar cautery. Ischemia of this segment of spinal cord was thus produced followed by paraplegia. The pathological findings of this spinal cord segment were softening and necrosis. The establishment of this animal model of segmental spinal cord ischemia is beneficial to scientific research in basic medicine and clinical practice.

MeSH terms

  • Animals
  • Disease Models, Animal*
  • Dogs
  • Female
  • Ischemia / complications*
  • Male
  • Paraplegia / etiology*
  • Spinal Cord / blood supply*