Ionic liquid-phase synthesis of 1,5-disubstituted 1,2,3-triazoles

Shinichi Koguchi; Kazuki Izawa

doi:10.1021/co500065e

Ionic liquid-phase synthesis of 1,5-disubstituted 1,2,3-triazoles

ACS Comb Sci. 2014 Aug 11;16(8):381-5. doi: 10.1021/co500065e. Epub 2014 Jul 23.

Authors

Shinichi Koguchi¹, Kazuki Izawa

Affiliation

¹ Department of Chemistry, Tokai University , 4-1-1 Kitakaname, Hiratsuka, Kanagawa 259-1292 Japan.

PMID: 25036551
DOI: 10.1021/co500065e

Abstract

A simplified ionic liquid-phase synthesis of 1,5-disubstituted 1,2,3-triazole was developed. Nineteen 1,5-disubstituted 1,2,3-triazoles were successfully obtained by merely washing the ionic liquid phase with ether, thus avoiding the need for intermediate purification.

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Benzyl Compounds / chemistry
Chemistry Techniques, Synthetic
Ionic Liquids / chemistry*
Triazoles / chemical synthesis*
Triazoles / chemistry

Substances

Benzyl Compounds
Ionic Liquids
Triazoles
benzyl chloride