[Mid-term results after complete surgical correction of transposition of the great arteries]

Srp Arh Celok Lek. 2014 May-Jun;142(5-6):306-13. doi: 10.2298/sarh1406306p.
[Article in Serbian]

Abstract

Introduction: Arterial switch operation (ASO) is a cardiosurgical method of choice for complete anatomical correction of transposition of great arteries. Improvement of this procedure has made considerably improved the outcome and long-term prognosis of children born with this complex congenital heart disease.

Objective: The aim of this study was to estimate the success rate of ASO through retrospective analysis of mortality and late complications.

Methods: This study included 57 children operated from 1st January 2005 until 31st December 2009. Parameters that could influence the outcome of surgery were investigated. The following late complications were investigated: neopulmonary artery stenosis, neoaortic stenosis and regurgitation, as well as clinical signs of heart failure.

Results: Early postoperative mortality was 15.8% (9/57 patients). During follow-up (8 to 72 months, average 36.5 months) there were no lethal outcomes. On the last echocardiography examination, 73.2% patients had neoaortic regurgitation and 67.4% patients had neopulmonary regurgitation, but all of them were mild in intensity. Neopulmonary stenosis had 32.6% of patients, but only two had moderate or severe stenosis. No one had ischemic ECG changes. Three reinterventions were performed due to serious residual problems: surgical correction of neoaortic stenosis, surgical correction of neopulmonary stenosis and transcatether balloon dilatation for aortic recoarctation. At the end of the follow-up period, only one of 46 consistently followed patients had signs of heart failure which required therapy (2.2%), while the majority of patients were without any symptoms and with good effort tolerance.

Conclusion: Arterial switch operation has been successfully performed at our institution, with acceptable perioperative mortality and excellent late outcome.

MeSH terms

  • Aorta / diagnostic imaging
  • Aorta / surgery
  • Child
  • Child, Preschool
  • Echocardiography
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Infant, Newborn
  • Male
  • Pilot Projects
  • Postoperative Complications / mortality
  • Retrospective Studies
  • Risk Factors
  • Transposition of Great Vessels / diagnostic imaging
  • Transposition of Great Vessels / mortality
  • Transposition of Great Vessels / surgery*