Stem cells: Reprogramming finds its niche

Daniel Lucas; Paul S Frenette

doi:10.1038/nature13516

Stem cells: Reprogramming finds its niche

Nature. 2014 Jul 17;511(7509):301-2. doi: 10.1038/nature13516. Epub 2014 Jul 2.

Authors

Daniel Lucas¹, Paul S Frenette²

Affiliations

¹ Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.
² Ruth L. and David S. Gottesman Institute for Stem Cell and Regenerative Medicine Research, Albert Einstein College of Medicine, New York, New York 10461, USA.

Abstract

Production of blood stem cells from reprogrammed adult cells is notoriously difficult. It emerges that a supportive microenvironment may be crucial for their efficient generation

Publication types

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MeSH terms

Animals
Cellular Microenvironment*
Cellular Reprogramming*
Endothelial Cells / cytology*
Female
Hematopoietic Stem Cells / cytology*
Humans
Multipotent Stem Cells / cytology*

Abstract

Publication types

MeSH terms

Grants and funding