C-H arylation of azaheterocycles: a direct ligand-free and Cu-catalyzed approach using diaryliodonium salts

Org Biomol Chem. 2014 Sep 7;12(33):6340-4. doi: 10.1039/c4ob01061b.

Abstract

An efficient and high yielding Cu-catalyzed direct C-H arylation of azaheterocycles including oxadiazoles, thiadiazoles, benzoxazoles and benzothiazoles has been achieved by employing easily accessible diaryliodonium salts.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aza Compounds / chemical synthesis*
  • Aza Compounds / chemistry
  • Catalysis
  • Copper / chemistry*
  • Heterocyclic Compounds / chemical synthesis*
  • Heterocyclic Compounds / chemistry
  • Molecular Structure
  • Onium Compounds / chemistry*
  • Salts / chemistry
  • Stereoisomerism

Substances

  • Aza Compounds
  • Heterocyclic Compounds
  • Onium Compounds
  • Salts
  • Copper