Abstract
The racial/ethnic disparities in DNA methylation patterns indicate that molecular markers may play a role in determining the individual susceptibility to diseases in different ethnic groups. Racial disparities in DNA methylation patterns have been identified in prostate cancer, breast cancer and colorectal cancer and are related to racial differences in cancer prognosis and survival.
Keywords:
Cancer; DNA methylation; Individual susceptibility; Racial/ethnic disparities.
Copyright © 2014. Published by Elsevier B.V.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Breast Neoplasms / ethnology
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Breast Neoplasms / genetics
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Breast Neoplasms / mortality
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Colorectal Neoplasms / ethnology
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Colorectal Neoplasms / genetics
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Colorectal Neoplasms / mortality
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DNA Methylation*
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Ethnicity*
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Female
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Humans
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Lung Neoplasms / ethnology
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Lung Neoplasms / genetics
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Lung Neoplasms / mortality
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Male
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Neoplasms / ethnology*
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Neoplasms / genetics*
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Neoplasms / mortality
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Prostatic Neoplasms / ethnology
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Prostatic Neoplasms / genetics
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Prostatic Neoplasms / mortality
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Racial Groups*